AI Agents to Become Ethereum’s Biggest Power User, Coinbase Developers Predict

August 14, 2025 – Coinbase developers believe AI agents could soon become Ethereum’s biggest power user, marking a major shift in how the blockchain is utilized. These autonomous agents, powered by artificial intelligence, can transact without human input, potentially revolutionizing e-commerce and other industries on Ethereum.

How AI Agents Could Transform Ethereum

According to Coinbase’s Kevin Leffew and Lincoln Murr, AI agents Ethereum will be capable of processing stablecoin payments entirely on their own. The HTTP 402 web standard, combined with Ethereum Improvement Proposal 3009, enables these systems to send and receive funds automatically.

This innovation could allow AI-powered applications to pay for cloud services, autonomous vehicles to fund their operations, or AI models to buy data and computational power instantly. By removing the need for human intermediaries, AI agents Ethereum could operate faster and more efficiently than traditional systems.

Why Ethereum Fits This Role

Leffew and Murr argue that Ethereum’s trustless settlement layer makes it the perfect environment for AI agents Ethereum. With atomic payment capability, programmable policy enforcement, and composable wallet integration, the blockchain can handle autonomous transactions securely and reliably.

Current Use Cases

Developers are already running experiments. Hyperbolic Labs has integrated HTTP 402 into its language model, while Prodia Labs uses AI agents Ethereum to generate media autonomously. These tests demonstrate how autonomous economic loops can function without direct human oversight.